Evaluation of an enzymic procedure for the measurement of acetaminophen.
نویسندگان
چکیده
We evaluated a new method for measurement of acetaminophen. From acetaminophen, acetate and p-aminophenol are enzymically produced, and the latter product is determined colorimetrically by reaction with o-cresol and ammoniacal copper sulfate. The method is rapid and precise, and results compare well with those by spectrophotometric and liquid-chromatographic techniques. Major metabolites of acetaminophen, some commonly used drugs, or phenolic substances that may be present in patients with liver or renal disease do not interfere.
منابع مشابه
Antinociceptive effect of acetaminophen in low frequency tail shock vocalization test in male NMRI rats
The present study was a protocol for investigation of the effect of acetaminophen (i.p.) on pain induced by electrical stimulation. We used tail shock vocalization (TSV) test for measurement of the pain. In this test, the animals were restrained and stimulated by two electrode implanted on the middle of the animal’s tail. The latency from stimulation of the tail till vocalization of the animal ...
متن کاملAntinociceptive effect of acetaminophen in low frequency tail shock vocalization test in male NMRI rats
The present study was a protocol for investigation of the effect of acetaminophen (i.p.) on pain induced by electrical stimulation. We used tail shock vocalization (TSV) test for measurement of the pain. In this test, the animals were restrained and stimulated by two electrode implanted on the middle of the animal’s tail. The latency from stimulation of the tail till vocalization of the animal ...
متن کاملComparative evaluation of alveolar bone level measurement pre and at gingival surgery
Comparative evaluation of alveolar bone level measurement pre and at gingival surgery Dr. R. Shariatmadar Ahmadi* - Dr. KH. Mani Kashani** - Dr. N. Dorri*** * - Assistant Professor of Periodontics Dept. Faculty of Dentistry – Hamedan University of Medical Sciences. **- Assistant Professor of MSPH Dept. – Faculty of Medicine – Hamedan University of Medical Sciences. *** - Dentist. Background and...
متن کاملIn vitro capacity and in vivo antioxidant potency of sedimental extract of Tinospora cordifolia in streptozotocin induced type 2 diabetes
Objective: The role of herbs against the free radicals have been put forth recently in combating many diseases. The aim of this study was to elucidate the in vitro capacity and in vivo antioxidant properties of sedimental extract of Tinospora cordifolia (SETc). Materials and Methods: SETcwas subjected to in vitro chemical analysis such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), nitric oxide, hydr...
متن کاملElectrochemical Synthesis and Kinetic Evaluation of Electrooxidation of Acetaminophen in the Presence of Antidepressant Drugs
With the aim of obtaining information about drug-drug interaction (DDI) between acetaminophen and some of antidepressant drugs (fluoxetine, sertraline and nortriptyline), in the present work we studied the electrochemical oxidation of acetaminophen (paracetamol) in the presence of these drugs by means of cyclic voltammetry and Controlled-potential coulometry. The reaction between N-acetyl-p-ben...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical chemistry
دوره 29 2 شماره
صفحات -
تاریخ انتشار 1983